Surgery-Related Factors and Local Recurrence of Wilms Tumor in National Wilms Tumor Study 4
نویسندگان
چکیده
منابع مشابه
MiR-21 Expression in Wilms’ Tumor
Background and Objective: Wilms’ tumor (WT) is the most common genitourinary tract tumor in children. MicroRNAs (miRNAs) are small non-coding RNAs; their role in the pathogenesis of many types of human cancers has been identified. We aimed to evaluate the expression of miR-21, a well-known oncomir, in WT tissue samples which is a very common urinary tract malignancy in children...
متن کاملTreatment of Wilms' tumor. Results of the Third National Wilms' Tumor Study.
The Third National Wilms' Tumor Study sought to reduce treatment for low-risk patients and find better chemotherapy for those at high risk for relapse. Eligible patients (1439) were randomized according to stage (I-IV) and histology (favorable [FH] or unfavorable [UH]), and contributed data to survival and relapse-free survival (RFS) analyses. Four-year (postnephrectomy) survival percentages an...
متن کاملAge distribution of Wilms' tumor: report from the National Wilms' Tumor Study.
Median ages at diagnosis were 36.5 and 42.5 mo for 1523 males and 1678 females with unilateral Wilms' tumor registered between October 1969 and December 1985; they were 23.5 mo and 30.5 mo for 100 males and 141 females with bilateral disease. The median age for multicentric, unilateral cases was intermediate between the bilateral and unicentric medians. Patients with hemihypertrophy in addition...
متن کاملThe management of synchronous bilateral Wilms tumor: a report from the National Wilms Tumor Study Group.
OBJECTIVE To provide guidelines for future trials, we reviewed the outcomes of children with synchronous bilateral Wilms tumors (BWT) treated on National Wilms Tumor Study-4 (NWTS-4). METHODS NWTS-4 enrolled 3335 patients including 188 patients with BWT (5.6%). Treatment and outcome data were collected. RESULTS Among 188 BWT patients registered with NWTS-4, 195 kidneys in 123 patients had i...
متن کاملEvaluation of CD133 and CD56/NCAM expression in Wilms tumor and their association with prognostic factors
Objective(s): To validate certain markers for cancer stem cell populations and their clinical importance in Wilms tumor (WT)Materials and Methods: Immunohistochemical study for CD133 and CD56/NCAM was performed on forty-six cases of WT that were diagnosed between 1999 and 2015, and the association of these markers with survival and progn...
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ژورنال
عنوان ژورنال: Annals of Surgery
سال: 1999
ISSN: 0003-4932
DOI: 10.1097/00000658-199902000-00019